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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Genes Brain Behav. 2017 Apr 4;16(6):592–600. doi: 10.1111/gbb.12378

Figure 2. Comparisons between Magel2 knockout mice and wildtype littermates in the elevated plus maze.

Figure 2

(a) Male Magel2 knockout mice (grey bar) show a significantly increased amount of time spent in the open arm when compared to wildtype littermate mice (black bar) (unpaired t-test). Magel2 knockout mice (hashed grey bar) showed no difference in amount of time spent in the closed arm, when compared to wildtype littermates (hashed black bar) (unpaired t-test). (b) Female Magel2 knockout mice (grey bar) show a significantly increased amount of time spent in the open arm when compared to wildtype littermate mice (black bar) (unpaired t-test). Female Magel2 knockout mice (hashed grey bar) showed a significantly reduced amount of time spent in the closed arm, when compared to wildtype littermates (hashed black bar) (unpaired t-test). (c) Male Magel2 knockout mice (grey bar) show no difference in the number of entries into the open arm compared to wildtype littermate mice (black bar) (unpaired t-test). (d) Female Magel2 knockout mice (grey bar) show a significantly increased number of entries into the open arm when compared to wildtype littermate mice (black bar) (unpaired t-test). Total assay time = 10 minutes. n=20 per genotype per sex. *, p<0.05; ****, p<0.0001.