Table 3.
Deformation measurements over the first week of age.
| Day 1 | Day 2 | Day 5 – 7 | p | |
|---|---|---|---|---|
| Entire cohort | ||||
| Number of infants | 132 | 132 | 98 | |
| LV GLS (%) | −18.4 ± 3.8 | −20.5 ± 3.1* | −21.8 ± 3.3* † | <0.001 |
| LV GLSRs (1/s) | −1.8 ± 0.4 | −2.1 ± 0.4* | −2.4 ± 0.4* † | <0.001 |
| IVS GLS (%) | −17.7 ± 2.1 | −17.9 ± 2.1 | −18.4 ± 2.1*† | <0.001 |
| IVS GLSR (1/s) | −1.7 ± 0.2 | −1.8 ± 0.2 | −1.9 ± 0.2† | 0.16 |
| RV FWLS (%) | −18.8 ± 4.7 | −20.1 ± 5.1 | −21.1 ± 4.7 | 0.05 |
| RV FWLSRs (1/s) | −2.0 ± 0.6 | −2.3 ± 0.7* | −2.8 ± 0.6* † | <0.001 |
| Healthy uncomplicated cohort | ||||
| Number of infants | 65 | 65 | 36 | |
| LV GLS (%) | −18.4 ± 3.5 | −20.3 ± 3.2* | −20.7 ± 3.0 † | <0.001 |
| LV GLSRs (1/s) | −1.8 ± 0.3 | −2.1 ± 0.3* | −2.3 ± 0.4 † | <0.001 |
| IVS GLS (%) | −17.7 ± 2.1 | −18.0 ± 2.1 | −18.4 ± 2.1*† | <0.001 |
| IVS GLSR (1/s) | −1.7 ± 0.2 | −1.8 ± 0.2 | −1.9± 0.2† | 0.12 |
| RV FWLS (%) | −18.1 ± 4.0 | −20.3 ± 3.2 | −20.5 ± 3.2* | 0.02 |
| RV FWLSRs (1/s) | −1.9 ± 0.5 | −2.2 ± 0.6 | −2.7 ± 0.7† | 0.004 |
Values are presented as mean (standard deviation). One way ANOVA with repeated measures was used to assess the change in values over time.
= p < 0.05 compared with previous day measurement;
= p < 0.05 compared with Day 1 measurement (with Bonferroni adjustment).
RV, right ventricle; LV, left ventricle; IVS, interventricular septum
FWLS, free wall longitudinal strain; FWLSRs, free wall longitudinal systolic strain rate
GLS, global longitudinal strain; GLSRs, global systolic longitudinal strain rate