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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Xenobiotica. 2017 Jan 3;47(11):989–997. doi: 10.1080/00498254.2016.1250292

Figure 5.

Figure 5

Gene expression of efflux transporters in intestinal cells treated with steroid hormones and metabolites. mRNA expression was quantified in LS174T-FXR cells and treated with vehicle (CON, set to 1.0), estradiol (E2, 0.1 μM), progesterone (PRG, 1 μM) or epiallopregnanolone-sulfate (PM5S, 7 μM) for 24 hours. Data were normalised to vehicle and presented as mean relative expression ± SE (n=3 independent experiments). Asterisks (*) represent statistically significant difference (p ≤ 0.05) compared with vehicle-treated cells.