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. 2005 Feb 24;33(4):1162–1168. doi: 10.1093/nar/gki239

Figure 1.

Figure 1

Editing in FLNA transcripts. (a) Some of the publicly available expressed sequences covering this gene, together with the corresponding genomic sequence. A total of 226 sequences are available for this locus, 23 of which are edited. (b) Results of sequencing experiments. Matching human DNA and cDNA RNA sequences for human brain and lung tissues. Editing is characterized by a trace of guanosine in the cDNA RNA sequence, where the DNA sequence exhibits only adenosine signals. Sequencing data for more tissues are available as Supplementary Material. Note the variety of tissues showing editing and the variance in the relative intensity of the edited guanosine signal. (c) Sequences of individually cloned fragments from matching DNA and RNA of mouse brain tissues and chicken brain and liver tissues. Only part of the data is shown. A total of 20 mouse brain cDNA clones, 10 chicken brain and 9 chicken liver cDNA clones were sequenced, out of which four, seven and one sequence showed editing events, respectively. Similar results for the other two substrates are provided as Supplementary Material.