Table 2.
Results of positive selection tests for interleukin-32 gene
| Model | Parameter estimates1) | lnL | LRTs | Positive selection sites |
|---|---|---|---|---|
| Model 1 | p0 = 0.638, p1 = 0.361 ω0 = 0.317, ω1 = 1.000 |
−2,445.220 | 0.791 | NEB: Not allowed |
| Model 2 | p1 = 0.649, p2 = 0.287, p3 = 0.062 ω1 = 0.336, ω2= 1.000, ω3= 1.749 |
−2,444.825 | BEB: | |
| Model 7 | p = 1.257, q = 1.077 | −2,443.730 | 4.318 | NEB: Not allowed |
| Model 8 | p0 = 0.875, p = 1.797, q = 2.009 (p1 = 0.124) ω = 1.628 | −2,441.571 | BEB: 2C, 6A, 10L, 11K, 23Q, 30S, 49S, 55D 75E, 89S |
LnL, log likelihood; LRT, likelihood ratio; NEB, naive empirical bayes; BEB, bayes empirical bayes.
1)
ω, the ratio of nonsynonymous-to-synonymous substitutions; p0, purifying selection; p2, neutral selection, p3, positive selection substitution ratio for all sites; p and q, the β distribution parameters.
*
p>95%;
**
p>99%.