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Modified branched peptide with a histidine-rich tail enhances gene transfection in MDA-MB-435 cells. MDA-MB-435 cells were transfected with PCI-Luc in complex with one of the four HK branched peptides: (i) H3K4b, (ii) H3K4bT, (iii) H2K4b and (iv) H2K4bT. In transfecting these cells, the peptides with a histidine-rich tail (H3K4bT and H2K4bT) were more effective than their counterparts without the tail. *, P < 0.001; H3K4bT versus H3K4b; H2K4bT versus H2K4b; t-test.
