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Comparison of gene delivery carriers in which the histidine-rich tail of H2K4bT has been replaced
| Carrier | Groups | % Transfection |
|---|---|---|
| H2K4bT | -HHHHNHHHHN | 100 |
| H2K4bNLS1 | -GNYNNQSSNFGPMKGGN | 33 |
| H2K4bNLS2 | -PKKKRKV | 8 |
| H2K4bRGD | -GRGD | 25 |
All carriers have the same DNA-binding branches but they have different tails. H2K4bT had the highest transfection of a luciferase plasmid and other polymers transfection abilities were based on H2K4bT (expressed as % transfection of H2K4bT).
