Figure 1.

Group mean connectivity matrices visualized with Circos (Krzywinski et al., 2009). (A,B) Show the connectivity matrices for HbO₂ contrast from the NaCl and LPS groups, respectively. (C,D) Same as (A,B) but for HbR. Supra-threshold edges are shown (FDR-corrected p < 0.05). M, motor cortex; C, cingulate cortex; S, somatosensory cortex; R, retrosplenial cortex. Subscripts L and R indicate hemisphere side. Note the significant reduction in connectivity in animals exposed to inflammation with a larger effect on HbR contrast.