. 2017 Feb 8;36(7):1253–1259. doi: 10.1007/s10096-017-2916-9

Table 1.

GDH assays compared to culture

Assay	Finding	Culture		% Sensitivity (95% CI)	% Specificity (95% CI)	% PPV (95% CI)	% NPV (95% CI)
Assay	Finding	Positive	Negative	% Sensitivity (95% CI)	% Specificity (95% CI)	% PPV (95% CI)	% NPV (95% CI)
GDH EIA	Positive	37	1	88.1 (73.6–95.5)	99.6^a (97.5–100)	97.4^a (84,6–99.9)	98.1 (95.4–99.3)
GDH EIA	Negative	5	257	88.1 (73.6–95.5)	99.6^a (97.5–100)	97.4^a (84,6–99.9)	98.1 (95.4–99.3)
GDH CLIA	Positive	42	9	100 (89.6–100)	96.5 (93.3–98.3)	82.4 (68.6–91.1)	100^b (98.1–100)
GDH CLIA	Negative	0	249	100 (89.6–100)	96.5 (93.3–98.3)	82.4 (68.6–91.1)	100^b (98.1–100)

CLIA chemiluminescent immunoassays, EIA enzyme immunoassays, CI confidence interval, PPV positive predictive values, NPV negative predictive values

^aStatistically significantly higher than by CLIA

^bStatistically significantly higher than by EIA