Table 2.
Thirty-day mortality correlated to selected characteristics
Characteristic (n = 292) | n | Died (%) | OR (95% CI) | p-value | adj. OR (95% CI) | adj. p-value | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Male sex | 201 | 40 (19.9) | 0.59 (0.33–1.04) | 0.07 | 0.35 (0.17–0.74) | 0.006 | |||||||
Age 18–49 years | 22 | 2 (9.1) | 1.00 | ||||||||||
Age 50–59 years | 36 | 6 (16.7) | 2.00 (0.37–10.92) | 0.42 | 2.72 (0.39–19.08) | 0.31 | |||||||
Age 60–69 years | 62 | 14 (22.6) | 2.92 (0.61–14.03) | 0.18 | 3.21 (0.51–20.03) | 0.21 | |||||||
Age 70–79 years | 83 | 20 (24.1) | 3.17 (0.68–14.78) | 0.14 | 3.58 (0.58–22.17) | 0.17 | |||||||
Age ≥80 years | 89 | 25 (28.1) | 3.91 (0.85–17.95) | 0.08 | 6.60 (1.13–38.49) | 0.04 | |||||||
Comorbidity (n = 235) | |||||||||||||
Pulmonary disease | 49 | 18 (36.7) | 2.58 (1.29–5.14) | 0.01 | 3.05 (1.34–6.94) | 0.008 | |||||||
COPD | 24 | 8 (33.3) | 1.89 (0.76–4.69) | 0.20 | 0.61 (0.16–2.37) | 0.47 | |||||||
Cystic fibrosis | 1 | 0 (0.0) | |||||||||||
Heart disorder | 87 | 22 (25.3) | 1.33 (0.71–2.49) | 0.42 | 1.50 (0.64–3.51) | 0.35 | |||||||
Peripheral vascular disease | 55 | 13 (23.6) | 1.14 (0.56–2.34) | 0.71 | 2.26 (0.96–5.30) | 0.06 | |||||||
Vascular graft | 15 | 1 (6.7) | 0.24 (0.03–1.83) | 0.20 | 0.18 (0.02–1.69) | 0.13 | |||||||
Diabetes mellitus | 63 | 9 (14.3) | 0.49 (0.22–1.08) | 0.08 | 0.46 (0.22–0.96) | 0.04 | |||||||
Renal failure | 42 | 10 (23.8) | 1.12 (0.51–2.46) | 0.84 | 1.96 (0.74–5.17) | 0.18 | |||||||
Chronic liver disease | 9 | 3 (33.3) | 1.79 (0.43–7.40) | 0.42 | 1.27 (0.22–7.21) | 0.79 | |||||||
Neurological paresis | 3 | 1 (33.3) | 1.16 (0.12–11.36) | 1.00 | 7.61 (0.45–128.36) | 0.16 | |||||||
Immunosuppression | 52 | 11 (21.2) | 0.91 (0.43–1.93) | 0.85 | 0.75 (0.26–2.18) | 0.59 | |||||||
Chemotherapy in the last 6 months | 52 | 12 (23.1) | 1.05 (0.50–2.19) | 1.00 | 0.21 (0.07–0.66) | 0.007 | |||||||
Solid malignancy | 73 | 20 (27.4) | 1.55 (0.81–2.94) | 0.23 | 0.99 (0.37–2.68) | 0.98 | |||||||
Metastasis | 39 | 14 (35.9) | 2.33 (1.11–4.90) | 0.03 | 7.12 (2.32–21.79) | 0.001 | |||||||
Haematologic disease | 42 | 11 (26.2) | 1.63 (0.74–3.59) | 0.28 | 5.47 (1.85–16.17) | 0.002 | |||||||
Neutropaenia | 38 | 11 (28.9) | 1.51 (0.69–3.30) | 0.30 | 1.33 (0.41–4.28) | 0.63 | |||||||
AIDS | 1 | 0 (0.0) | |||||||||||
Burn wounds | 6 | 2 (33.3) | 1.77 (0.32–9.95) | 0.62 | 4.08 (0.45–36.68) | 0.21 | |||||||
Composite comorbidity score (n = 235) | |||||||||||||
Charlson score ≤4 | 44 | 4 (9.1) | 1.00 | ||||||||||
Charlson score 5–8 | 119 | 27 (22.7) | 2.93 (0.96–8.94) | 0.06 | 2.91 (0.95–8.92) | 0.06 | |||||||
Charlson score 9–12 | 49 | 13 (26.5) | 3.61 (1.08–12.08) | 0.04 | 3.67 (1.09–12.41) | 0.04 | |||||||
Charlson score ≥13 | 21 | 8 (38.1) | 6.15 (1.59–23.82) | 0.009 | 7.05 (1.79–27.86) | 0.005 | |||||||
Healthcare-related (n = 235) | |||||||||||||
Urinary catheter >1 week | 88 | 18 (20.5) | 0.87 (0.45–1.65) | 0.75 | 1.09 (0.50–2.39) | 0.82 | |||||||
Surgery last month | 48 | 9 (18.8) | 0.76 (0.34–1.69) | 0.56 | 0.98 (0.38–2.51) | 0.96 | |||||||
Hospitalised >1 week | 82 | 20 (24.4) | 1.21 (0.64–2.29) | 0.62 | 1.61 (0.76–3.41) | 0.22 | |||||||
Resident at nursing home | 33 | 8 (24.2) | 1.15 (0.48–2.72) | 0.82 | 1.16 (0.41–3.32) | 0.78 | |||||||
Polymicrobial infection | 90 | 22 (24.4) | 1.13 (0.62–2.02) | 0.68 | 2.52 (1.18–5.40) | 0.02 | |||||||
Origin of infection (n = 235) | |||||||||||||
Urinary tract | 82 | 12 (14.6) | 0.37 (0.18–0.75) | 0.005 | 0.28 (0.12–0.65) | 0.003 | |||||||
Respiratory tract | 44 | 17 (38.6) | 2.81 (1.38–5.70) | 0.003 | 2.81 (1.13–7.01) | 0.03 | |||||||
Wound | 38 | 12 (31.6) | 1.81 (0.84–3.90) | 0.13 | 1.99 (0.81–4.92) | 0.13 | |||||||
Central venous catheter | 9 | 0 (0.0) | |||||||||||
Other/unknown | 50 | 11 (22.0) | 0.99 (0.47–2.11) | 0.98 | 1.16 (0.47–2.83) | 0.75 |
Patient characteristics correlated to 30-day mortality and presented with odds ratio (OR), adjusted odds ratio (adj. OR) and 95% confidence interval (95% CI). The multivariable model contained age, sex, pulmonary disease, vascular graft, peripheral vascular disease, chemotherapy in the last 6 months, haematological diseases including malignancies, metastasis, diabetes mellitus and neurological paresis. Significant values are in bold font