Table 2.
Experimental endotoxemia modulates expression of unannotated lincRNAs
| Adipose Tissue | High Responder (n = 13) |
Low Responder (n = 12) |
||||
|---|---|---|---|---|---|---|
| FPKM percentile | 5th | 10th | 20th | 5th | 10th | 20th |
| DE lincRNAs, n | 9 | 5 | 2 | 0 | 0 | 0 |
| Monocytes | High Responder (n = 8) |
Low Responder (n = 7) |
||||
|---|---|---|---|---|---|---|
| FPKM percentile | 5th | 10th | 20th | 5th | 10th | 20th |
| DE lincRNAs, n | 61 | 51 | 26 | 4* | 2 | 1 |
The number of endotoxemia-induced differentially expressed (DE) unannotated lincRNAs with fold change ≥2, false discovery rate-adjusted P value <0.05 and presence in ≥80% of participants is shown at the 5th, 10th, and 20th percentile fragments per kilobase of exon per million fragments mapped (FPKM). The number of DE unannotated lincRNAs that are expressed above each percentile in either pre-LPS or post-LPS samples are shown in adipose tissue and monocytes. LPS, lipopolysaccharide.
*
In monocytes 4 of 4 unannotated lincRNA DE in low responders were also DE in the high-responder samples.