Coexpression of α-ENaC/ASIC1a produces high-conductance NSC channels. A: Western blot showing ASIC1a detection in FRT cells with and without α-ENaC. Although the blot is cropped, there are no other bands in the blot. B: conductance of channels found in patches on FRT cells transfected with GFP/dsRed vector only, GFP α-ENaC, or dsRed ASIC1a + GFP α-ENaC. C, top: representative traces from FRT cell transfected with GFP α-ENaC. Bottom: representative traces from FRT cells transfected with dsRed ASIC1a + GFP α-ENaC. Vp, voltage of the pipette.