Skip to main content
. 2017 Mar 23;312(6):L936–L944. doi: 10.1152/ajplung.00256.2016

Fig. 5.

Fig. 5.

Expressions of NOX4 and HDAC4 in IPF lung biopsy specimens. A: total RNA was isolated from lung biopsy specimens of IPF patients [n = 10; 3 patients with forced vital capacity (FVC) of 50–80% predicted and 7 patients with FVC of <50% predicted] or controls [very mild chronic obstructive pulmonary disease; COPD; Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage 1; n = 11]. NOX 4 mRNA expression was measured using real-time PCR and normalized to 18S. *P < 0.05 vs. control. B: immunohistochemistry localizing HDAC4 in IPF lung biopsy specimens. Scale bars are for the panoramic view 100 μm (bottom left), middle magnification 20 μm (top left), and high magnification 10 μm (top right and bottom right).