Fig. 6.
Capsazepine-mediated attenuation of acetylcholine-induced contraction of guinea pig tracheal rings. A: representative tracings of guinea pig tracheal ring contractile force receiving pretreatment with 100 µM capsazepine vs. vehicle. All rings were contracted with an EC50 concentration of acetylcholine calculated for each individual ring. B: quantification of contractile force 15 min after acetylcholine exposure (as a percentage of peak force). Capsazepine pretreatment significantly attenuated the maintenance of contractile force in guinea pig ASM. Values are means ± SE; n = 4 animals. ***P < 0.001 by Student’s t-test.