Table 3. Changes in the weight SDS and BMI SDS in girls with idiopathic central precocious puberty or early puberty following GnRHa treatment in 3 different BMI groups.
Normal weight (n=97) | Overweight (n=20) | Obesity ( n=12) | ||||
---|---|---|---|---|---|---|
Weight SDS | BMI SDS | Weight SDS | BMI SDS | Weight SDS | BMI SDS | |
Before Tx | 0.48±0.79 | 0.00±0.71 | 0.59±0.60 | 1.49±0.32 | 2.71±0.65 | 2.57±0.33 |
After 1 yr | 0.63±0.77 | 0.31±0.76a) | 1.67±0.67 | 1.67±0.45 | 2.59±0.89 | 2.44±0.74 |
After 2 yr | 0.51±0.77 | 0.34±0.72b) | 1.48±0.61 | 1.70±0.58 | 2.17±0.68 | 2.28±0.70 |
Values are presented as mean±standard deviation.
SDS, standard deviation score; BMI, body mass index; GnRHa, gonadotropin-releasing hormone agonist; Tx, treatment.
a)P<0.0001, before treatment vs. after treatment for 1 year. b)P<0.0001, before treatment vs. after treatment for 2 years.