Table I.
Dose assessments (in vitro)* obtained by the analysis of 20 lymphocyte PCC spreads per coded slide by each laboratory group.
| Group | Actual dose (Gy) | Estimated dose (Gy) | 95% LCL (Gy) | 95%UCL (Gy) |
|---|---|---|---|---|
| L0 | 0 | 0 | 0 | 0 |
| 0.5 | 0.48 | 0.42 | 0.56 | |
| 1.0 | 0.9 | 0.8 | 1.0 | |
| 2.0 | 1.8 | 1.6 | 2.0 | |
| 3.0 | 2.7 | 2.4 | 3.0 | |
| 4.0 | 3.5 | 3.0 | 4.0 | |
| 5.0 | 4.4 | 3.9 | 5.0 | |
| 6.0 | 5.1 | 4.5 | 5.8 | |
| L1 | 0 | 0 | 0 | 0 |
| 0.5 | 0.62 | 0.55 | 0.7 | |
| 1.0 | 1.1 | 1.0 | 1.3 | |
| 2.0 | 1.9 | 1.7 | 2.1 | |
| 3.0 | 2.8 | 2.5 | 3.2 | |
| 4.0 | 3.5 | 3.0 | 4.1 | |
| 5.0 | 4.2 | 3.7 | 4.8 | |
| 6.0 | 5.1 | 4.5 | 5.7 | |
| L3 | 0 | 0 | 0 | 0 |
| 0.5 | 0.2 | 0.1 | 0.3 | |
| 1.0 | 0.5 | 0.4 | 0.6 | |
| 2.0 | 1.2 | 1.1 | 1.4 | |
| 3.0 | 1.7 | 1.5 | 1.9 | |
| 4.0 | 1.7 | 1.5 | 1.9 | |
| 5.0 | 2.8 | 2.5 | 3.2 | |
| 6.0 | 3.6 | 3.2 | 4.1 | |
| L5 | 0 | 0 | 0 | 0 |
| 0.5 | 0.58 | 0.5 | 0.65 | |
| 1.0 | 0.8 | 0.7 | 0.9 | |
| 2.0 | 1.3 | 1.1 | 1.5 | |
| 3.0 | 2.1 | 1.8 | 2.4 | |
| 4.0 | 3.0 | 2.6 | 3.4 | |
| 5.0 | 3.6 | 3.1 | 4.0 | |
| 6.0 | 5.3 | 4.7 | 5.9 |
*
The dose estimates were obtained using a calibration curve generated at L0 following the irradiation of human lymphocytes (from 10 donors) to X-rays (200 kV, 4 mA). The dose response curve was found to be linear (α= 4.1 and β= 0.07).