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Impact of dalcetrapib (Dal) and anacetrapib (Ana) on rabbit and monkey plasma CETP activity and mass. CETP activity (A, B) and mass (C, D) were evaluated in rabbits (A, C) and monkeys (B, D) treated with dalcetrapib and anacetrapib. At the end of treatment, animal plasma was used for measurement of CETP activity and mass. Results are presented as mean ± SEM of n = 7–8 rabbits and n = 7 monkeys. *P < 0.05, ***P < 0.001 versus baseline values.
