TABLE 3.

Association of TM6SF2 SNP rs58542926-T with apoB-100 replicates in the independent FINRISK cohort (n = 2,196)

Replication Variable	n	β ± SE	Pa
ApoB-100, g/l
METSIM	6,929	−0.057 ± 0.0081	2.44 × 10−12
FINRISK	2,196	−0.029 ± 0.013	0.029
Tyrosine, mmol/l
METSIM	6,929	0.0021 ± 0.00039	6.53 × 10−8
FINRISK	2,196	0.0010 ± 0.00074	0.15

^aReplication analyses in both METSIM and FINRISK excluded for those with known diabetes and on lipid-lowering medication at time of enrollment. Linear regression models adjusted for age, sex (in FINRISK), BMI, current smoking status, and tyrosine (when apoB-100 was the outcome) and apoB-100 (when tyrosine was the outcome).