Table 2.
Baseline characteristics in TB patients in relation to unstable fasting blood glucose levels during the 6-month course of anti-TB treatment.
| Characteristics | Total N = 270 |
No. (%) with unstable FBG (N = 80) |
Univariate OR (95% CI) | Multivariate adjusted OR (95% CI) | P-value | |
|---|---|---|---|---|---|---|
| Total | 270 | 80 (29.6) | ||||
| Sex | Female | 91 | 21 (23.1) | Reference | ||
| Male | 179 | 59 (33.0) | 1.639 (0.919–2.923) | |||
| Age | < 20 | 22 | 5 (22.7) | Reference | ||
| 20–59 | 187 | 47 (25.1) | 1.141 (0.399–3.263) | |||
| ≥ 60 | 61 | 28 (45.9) | 4.210 (0.944–8.816) | |||
| TB Type |
Smear – | 187 | 54 (28.9) | Reference | ||
| Smear + | 68 | 21 (31.9) | 1.100 (0.602–2.013) | |||
| EPTB | 15 | 5 (33.3) | 1.231 (0.402–3.771) | |||
| Fever | No | 183 | 48 (26.2) | Reference | ||
| Yes | 87 | 32 (36.8) | 1.636 (0.948–2.820) | |||
| Haemoptysis | No | 246 | 71 (28.9) | Reference | ||
| Yes | 24 | 9 (37.5) | 1.479 (0.619–3.534) | |||
| HIV status | Negative | 142 | 49 (34.5) | Reference | ||
| Positive | 9 | 6 (66.7) | 3.796 (0.910–15.837) | 6.668 (1.245–35.706) | 0.027 | |
| Not-tested | 119 | 25 (21.0) | 0.505 (0.288–0.884) | 0.640 (0.308–1.332) | 0.233 | |
| Diabetes | No | 249 | 62 (24.9) | Reference | ||
| Yes | 21 | 18 (85.7) | 18.097 (5.156–63.515) | 17.016 (4.669–62.014) | < 0.0001 | |
| Liver diseases | No | 256 | 74 (28.9) | Reference | ||
| Yes | 14 | 6 (42.9) | 1.845 (0.619–5.500) | |||
| Smoking cigarettes/day |
0 | 186 | 47 (25.3) | Reference | ||
| 1–19 | 66 | 29 (43.9) | 2.318 (1.288–4.173) | 2.660 (1.374–5.150) | 0.004 | |
| ≥ 20 | 10 | 4 (40.0) | 1.972 (0.533–7.290) | 3.010 (0.623–14.551) | 0.170 | |
| Not | 8 | 0 (0) | ||||
| clear | ||||||
| Source of patients | TB clinic | 163 | 32 (19.6) | Reference | ||
| TB hospital | 107 | 48 (44.9) | 3.331 (1.396–5.731) | 2.422 (1.209–4.852) | 0.013 |
Notes: TB = tuberculosis; DM = diabetes mellitus; FBG = fasting blood glucose; CI: confidence intervals; smear + = smear-positive pulmonary TB; smear – = smear-negative pulmonary TB; EPTB = extra-pulmonary TB.
An unstable FBG was defined as a change in fasting blood glucose of more than 1.0 mmol/L between baseline and 2 months or 6 months during the 6-month anti-TB treatment.