Figure 1.

Overview of repetitive elements in the mouse genome. (A) Schematic diagram of a mitotic mouse chromosome illustrating the distribution of major (pericentric) and minor (centromeric) satellite repeats and of the various interspersed repetitive elements. (B) Summary description of repeat classes, highlighting repeat organization, length, copy number and overall abundance in the mouse genome. Specific primers (black arrows) were designed to generate PCR fragments from within the repetitive elements, thereby allowing a cluster analysis that detects the sum of chromatin modifications for a given repeat class. The sequences of these primers are indicated in Supplementary data. Although the entire repeat units are shown, most repetitive elements in the mouse genome are not full length (Waterston et al, 2002).