Table 4.
Factors associated with the risk of metachronous liver metastasis for stage III pancreatic cancer (univariate and multivariate cox regression model) (N = 707)
| Variable | Univariate analysis | Stepwise multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (≥60 vs. <60) | 0.78 | 0.60–1.02 | 0.0736 | 0.77 | 0.58–1.01 | 0.0555 |
| Sex (male vs. female) | 0.82 | 0.63–1.08 | 0.1534 | |||
| Smoking (yes vs. no) | 0.98 | 0.75–1.29 | 0.8878 | |||
| Alcohol (yes vs. no) | 0.93 | 0.63–1.39 | 0.7288 | |||
| Location (body/tail vs. head/neck) | 0.81 | 0.62–1.07 | 0.1367 | |||
| Diameter (≥20 vs. <20) | 1.62 | 1.02–2.59 | 0.0413 | 1.58 | 0.99–2.52 | 0.0542 |
| ALT or AST (elevated vs. normal) | 1.02 | 0.67–1.55 | 0.9162 | |||
| ALB (low vs. normal) | 1.03 | 0.72–1.47 | 0.8848 | |||
| CA19-9 (elevated vs. normal) | 1.15 | 0.81–1.62 | 0.4381 | |||