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. 2017 Jul 3;18:209. doi: 10.1186/s12882-017-0626-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Effect of TGF-ß administration on IMCD cells under normal osmotic concentration. TGF-ß administration for 48 h significantly upregulated Egr-1 mRNA expression by 2-fold (a) but had no effect on type III collagen expression (b). As compared to the effects of increased osmotic concentration, TGF-ß administration induced only a mild type IV collagen overexpression (c). Data are presented as mean ± SEM, n = 3/group. * p < 0.05 (Mann-Whitney test)