Table 3.
CYP3A haplotype distribution among pregnant women with uncomplicated Plasmodium falciparum infection in Tanzania
| CYP3Ahaplotype | CYP3A SNP combinations | Frequency (%) | |||
|---|---|---|---|---|---|
|
CYP3A4*1B
−392A>G |
CYP3A5 *3
g.6986A>G |
CYP3A5 *6
g.14690G>A |
CYP3A5 *7
27131_27132insT |
||
| GAGA | *1B | wt | Wt | wt | 34.2 |
| GAAA | *1B | wt | *6 | wt | 17.6 |
| GGA | 1B | *3 | Wt | wt | 13.3 |
| AAGA | wt | wt | Wt | wt | 11.4 |
| GAGT | *1B | wt | Wt | *7 | 11.0 |
| AGGA | wt | *3 | Wt | wt | 8.2 |
| AAAA | wt | wt | *6 | wt | 3.0 |
| AGGT | wt | wt | Wt | *7 | 1.3 |
wt wild type variant allele, SNP single-nucleotide polymorphism