Table 3.
Tmax and T1/2 (mean (SD)) of aripiprazole after administration of long acting injectable aripiprazole (Abilify Maintena®) and aripiprazole lauroxil (Aristada®)
| After single gluteal injection of aripiprazole 400 mg equivalents | After 4th gluteal injection of aripiprazole 300 mg equivalentsa | |||
|---|---|---|---|---|
| Aripiprazole LAI | Aripiprazole lauroxil | Aripiprazole LAI | Aripiprazole lauroxil | |
| Tmax (day) | 22 (4–22)b | 44.0 (11.7) | 6.5 (0.5–21.2)b | 21.1 |
| T1/2 (day) | 10.5 (3.9) | 18.0 (4.8) | 29.9 (8.0) | 29 (6) |
aPharmacokinetic parameters at steady-state. Data for the 400 mg equivalents is not available for aripiprazole lauroxil. For the purpose of comparison between two agents, data for the 300 mg equivalents is included
bReported as median (range)