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. 2017 Jul 4;17:58. doi: 10.1186/s12896-017-0368-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — PEG-FGF21 ameliorate plasma lipid metabolism significantly compared with FGF21 in DIO mice. The level of plasma Triglyceride measured after treatment with FGF21 and PEG-FGF21(a), Low-density lipoprotein (LDL) content in serum (b), and the level of total cholesterol (TCHO) measured in serum after treatment with FGF21 and PEG-FGF21 for 2 months (c); Values are means ± SEM. Statistics by two-tailed t-test: *P ≤ 0.05; vs DIO + FGF21.n = 10