Anti-peptide gp41 and anti-V3 titers. A. Serum IgG ELISA reactivity of HIVIS-DNA against HIV-1 envelope peptides representing HIV-1 subtypes A, B and C epitopes tested after HIVIS-DNA and two MVA-CMDR boost immunizations. B. Serum IgG ELISA reactivity of HIVISopt-DNA against HIV-1 envelope peptides representing HIV-1 subtypes A, B and C epitopes tested after HIVISopt-DNA and two MVA-CMDR boost immunizations. C. Serum IgG ELISA reactivity of MVA-CMDR against HIV-1 envelope peptides representing HIV-1 subtypes A, B and C epitopes was tested after two MVA-CMDR boost immunizations. D. Serum IgG ELISA reactivity in non-immunized mice against HIV-1 envelope peptides representing HIV-1 subtypes A, B and C epitopes. Absorbance values are given for serum dilutions of 120. + Blue color indicates components of HIVIS-DNA, yellow color indicates components of HIVISopt-DNA and red color indicates components of MVA-CMDR.