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. 2017 Jun 29;3(6):e00339. doi: 10.1016/j.heliyon.2017.e00339

Fig. 4.

Fig. 4

Virus neutralization results with sera from mice with high or low ELISA binding titers. A. Sera pooled from HIVIS-DNA, HIVISopt-DNA or MVA groups and naive mice were tested at dilutions 20, 60, 180 and 540 against HIV-1CRF01_AE strain 1525. B. Individual sera from HIVISopt-DNA boosted twice by MVA-CMDR were tested at dilutions 20, 60, 180 and 540 against HIV-1 subtype C strain J10687. Numbers 2B1-2B10 indicate single mouse identifications. RT measurements define viral replication, lower concentrations reflect a better neutralization. Blue color indicates components of HIVIS-DNA, yellow color indicates components of HIVISopt-DNA and red color indicates components of MVA-CMDR.