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Histopathology of the livers from the different experimental groups: (a) Mesosphaerum sidifolium essential oil (EOM) (50 mg/kg) - Portal space with a vasculobiliar triad; (b) EOM (150 mg/kg) - Anaplastic tumor cells, bordered by necrosis of the hepatic tissue; (c) EOM (100 mg/kg) - Reactive hyperplasia of Kuppfer cells; (d) 5-FU (25 mg/kg) - Lymphocytes at the moderate level compromising the portal space. Hematoxylin-eosin (100 or 400 x)
