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. 2017 Jun 24;13:569–574. doi: 10.1016/j.dib.2017.06.035

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© 2017 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 3 — Collagen deposition after intramyocardial transplantation of MACS® MicroBeads and stem cells. MACS® MicroBeads or 1×10⁵ CD133⁺ and CD271⁺ stem cells were intramyocardially injected into SCID bg mice after myocardial infarction (MI). Three weeks after transplantation, fibrotic events at the infarction border zone were analyzed by histological staining of heart slices with Sirius Red and Fast Green FCF. For control, untreated infarction (MI-C) and SHAM operation were used. Collagen deposition is expressed as the ratio of collagen deposition to myocardial tissue in percentage. Values are presented as mean±SEM; n = 7 (MI-C; MI-CD133 manually isolated; MI-CD271 manually isolated); n = 6 (MI-MACS MicroBeads; MI-CD133 automatically isolated; SHAM); ∗ and # = p ≤ 0.05; ∗∗ and ## = p ≤ 0.01; ∗∗∗ and ### = p ≤ 0.001 vs. MI-C (∗) or MI-MACS MicroBeads (#).