Table 3.
Regions showing a positive correlation between fractional anisotropy and intelligence quotient in the cerebral palsy group.
| Cluster number | Cluster size (mm3) | Mean FA (SD) (CP/controls) | Anatomical regions |
||
|---|---|---|---|---|---|
| JHU white matter atlas | Harvard-Oxford cortical structural atlas | ||||
| 1 | 143,218 | 0.393 (0.099)/ 0.418 (0.105) |
MS | Genu, body and splenium of corpus callosum Column and body of fornix Middle cerebellar peduncle |
|
| B |
Fornix (cres) Cerebral peduncle Posterior thalamic radiation (include optic radiation) Posterior limb and retrolenticular part of internal capsule Superior and posterior corona radiata External capsule Cingulum (cingulate gyrus and hippocampus) Superior longitudinal fasciculus Superior fronto-occipital fasciculus (could be a part of anterior internal capsule) Anterior limb of internal capsule |
Insular cortex Superior,middle and inferior (pars opercularis) frontal gyrus Precentral gyrus Superior temporal gyrus (anterior and posterior division) Middle temporal gyrus (posterior division and temporo-occipital part) Postcentral gyrus Superior parietal lobe Supramarginal gyrus (anterior and posterior division) Cingulate gyrus (anterior and posterior division) Precuneous cortex Parahippocampal gyrus (anterior division) Supplementary motor cortex Central and parietal opercular cortex Planum polare Planum temporale Lateral occipital cortex (superior division) Angular gyrus Heschl's gyrus (includes H1 and H2) |
|||
| LH | Frontal operculum cortex | ||||
| RH | Tapetum Sagittal stratum (include inferior longitudinal fasciculus and inferior fronto-occipital fasciculus) |
Inferior frontal gyrus (pars triangularis) Cuneal cortex Parahippocampal gyrus (posterior and anterior division) Temporal fusiform cortex (posterior division) Temporal occipital fusiform cortex Inferior temporal gyrus (posterior division and temporo-occipital part) |
|||
| 2 | 3359 | 0.432 (0.087)/ 0.443(0.093) |
LH | Posterior thalamic radiation (include optic radiation) | Intracalcarine cortex Lingual gyrus Occipital fusiform gyrus Temporal occipital fusiform cortex |
| 3 | 1184 | 0.310 (0.036)/ 0.322 (0.037) |
B |
Frontal orbital cortex Subcallosal cortex |
|
| 4 | 890 | 0.314 (0.042)/ 0.315 (0.042) |
LH |
Frontal orbital cortex Subcallosal cortex |
|
| 5 | 147 | 0.349 (0.069)/ 0.352 (0.070) |
LH | Superior frontal gyrus | |
| 6 | 54 | 0.272 (0.024)/ 0.296 (0.028) |
LH | Lateral occipital cortex (superior division) | |
B: bilateral; CP: cerebral palsy; FA: fractional anisotropy; JHU: John Hopkins University; LH: left hemisphere; MS: medial structure; RH: right hemisphere; SD: standard deviation. Discrepancies between fractional anisotropy and mean diffusivity results are indicated as follows. Bold indicates regions that are significant with both fractional anisotropy and mean diffusivity. Italics indicate regions that only show the same result between fractional anisotropy and mean diffusivity in one hemisphere.