Table 4.
Regions showing a negative correlation between fractional anisotropy and cognitive flexibility in the cerebral palsy group.
| Cluster number | Cluster size (mm3) | Mean FA (SD) (CP/controls) | Anatomical regions |
||
|---|---|---|---|---|---|
| JHU white matter atlas | Harvard-Oxford cortical structural atlas | ||||
| 1 | 20,951 | 0.450 (0.104)/ 0.479 (0.110) |
MS | Body and splenium of corpus callosum | |
| B | Posterior corona radiata | Cingulate gyrus (posterior division) | |||
| LH | Tapetum Retrolenticular part of internal capsule Posterior thalamic radiation (include optic radiation) Cingulum (cingulate gyrus) Superior longitudinal fasciculus |
Precentral gyrus Postcentral gyrus Lingual gyrus Occipital fusiform gyrus Supramarginal gyrus (anterior and posterior division) Intracalcarine cortex Supracalcarine cortex Cuneal cortex Planum temporale Inferior temporal gyrus (temporo-occipital part) |
|||
| 2 | 245 | 0.379 (0.070)/ 0.392 (0.074) |
RH |
Lateral occipital cortex (superior division) Superior parietal lobe Precuneous cortex |
|
| 3 | 69 | 0.379 (0.070)/ 0.392 (0.074) |
RH | Superior parietal lobe | |
| 4 | 54 | 0.453 (0.080)/ 0.474 (0.085) |
RH | Cingulate gyrus (anterior division) | |
B: bilateral; CP: cerebral palsy; FA: fractional anisotropy; JHU: John Hopkins University; LH: left hemisphere; MS: medial structure; RH: right hemisphere; SD: standard deviation. Discrepancies between fractional anisotropy and mean diffusivity results are indicated as follows. Bold indicates regions that are significant with both fractional anisotropy and mean diffusivity. Italics indicate regions that only show the same result between fractional anisotropy and mean diffusivity in one hemisphere.