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. 2017 Jul 3;149(7):689–701. doi: 10.1085/jgp.201611744

Table 2. Effect of forskolin on the parameters of photoresponse and dark current noise.

Species SPRNR SPRForsk SPRForsk/ SPRNR SDNR SDForsk SDForsk/SDNR S/NNR S/Nforsk S/Nforsk/S/NNR νdeNR νdeForsk νdeForskdeNR
pA pA pA pA µm−3s−1 × 10−6 µm−3s−1 × 10−6
Frog 0.48 ± 0.09 (9) 0.87 ± 0.13 (9) 2.1 ± 0.30a (9) 0.20 ± 0.01 (8) 0.21 ± 0.02 (8) 1.03 ± 0.06 (8) 2.30 ± 0.42 (8) 4.17 ± 0.57 (8) 2.08 ± 0.29a (8) 22 ± 2.5 (5) 21 ± 3.4 (5) 0.97 ± 0.19 (5)
Toad 0.84 ± 0.13 (10) 1.69 ± 0.18 (10) 2.32 ± 0.35a (10) 0.23 ± 0.02 (10) 0.28 ± 0.02 (10) 1.20 ± 0.05a (10) 3.36 ± 0.53 (9) 6.32 ± 0.8 (9) 2.10 ± 0.34a (9) 9.3 ± 1.8 (6) 9.2 ± 1.0 (6) 1.09 ± 0.13 (6)

SPRNR and SPRForsk are amplitudes of SPRs in normal Ringer and in forskolin-containing solution, respectively. SD is standard deviation of continuous dark noise. S/N = SPR/SD stands for SNR. νdeNR and νdeForsk are rates of discrete dark events expressed as the number of events per second per µm3 of the rod outer segment volume.

a

Statistically significant effects of forskolin perfusion (P < 0.05).