Table 2. Effect of forskolin on the parameters of photoresponse and dark current noise.
Species | SPRNR | SPRForsk | SPRForsk/ SPRNR | SDNR | SDForsk | SDForsk/SDNR | S/NNR | S/Nforsk | S/Nforsk/S/NNR | νdeNR | νdeForsk | νdeForsk/νdeNR |
---|---|---|---|---|---|---|---|---|---|---|---|---|
pA | pA | pA | pA | µm−3s−1 × 10−6 | µm−3s−1 × 10−6 | |||||||
Frog | 0.48 ± 0.09 (9) | 0.87 ± 0.13 (9) | 2.1 ± 0.30a (9) | 0.20 ± 0.01 (8) | 0.21 ± 0.02 (8) | 1.03 ± 0.06 (8) | 2.30 ± 0.42 (8) | 4.17 ± 0.57 (8) | 2.08 ± 0.29a (8) | 22 ± 2.5 (5) | 21 ± 3.4 (5) | 0.97 ± 0.19 (5) |
Toad | 0.84 ± 0.13 (10) | 1.69 ± 0.18 (10) | 2.32 ± 0.35a (10) | 0.23 ± 0.02 (10) | 0.28 ± 0.02 (10) | 1.20 ± 0.05a (10) | 3.36 ± 0.53 (9) | 6.32 ± 0.8 (9) | 2.10 ± 0.34a (9) | 9.3 ± 1.8 (6) | 9.2 ± 1.0 (6) | 1.09 ± 0.13 (6) |
SPRNR and SPRForsk are amplitudes of SPRs in normal Ringer and in forskolin-containing solution, respectively. SD is standard deviation of continuous dark noise. S/N = SPR/SD stands for SNR. νdeNR and νdeForsk are rates of discrete dark events expressed as the number of events per second per µm3 of the rod outer segment volume.
Statistically significant effects of forskolin perfusion (P < 0.05).