Table 4. Comparing parameters of the transduction cascade derived from MEM and from fitting continuous noise spectra, as in Fig. 7.

Parameter		Units	NR				Forsk.
			MEM	Noise 1	Noise 2		MEM	Noise 1	Noise 2
Dark cGMP turnover rate	Pd	s−1	0.625	5.5	0.6		0.21	1.6	0.25
Fast cytoplasmic Ca2+ turnover rate	β	s−1	3.2	0.45	6		2.2	0.25	2
PDE subunit activity, turnovers per ROS volume	â	µM⋅s−1	4.7 × 10−4	1.45 × 10−5	4 × 10−5		4.7 × 10−4	1.65 × 10−5	6.8 × 10−5
Rate of inactivation of spontaneously activated PDE	kE	s−1	-	1.9	7		-	4	4.75

Columns labeled Noise 1 refer to good-quality fits (curves 1 in Fig. 7, A and B), and those labeled Noise 2 refer to poor fits (curves 2 in Fig. 7, A and B).