Figure 12.

Figure depicting (a) building blocks consisting of a peptide attached to an aromatic ring. Building blocks 1 and 2 differ only in the nature of the penultimate amino acid. (b) The building blocks can form macrocycles of different sizes upon oxidation, which can exchange building blocks with each other. (c) Schematic representation showing how building blocks oxidize to form macrocycles that in turn form stacks due to β-sheet formation. Stacks grow from their ends and fragment upon agitation, leading to more fiber ends and faster growth [52].