A) Change in plaque composition in low, intermediate, and high WSS segments over 6 months. WSS: wall shear stress (from Samady et al. [35]). B) Change in plaque strain in tertiles of WSS over 6 months. (# denotes that change is significantly different from zero at a p <0.05 level) (Reprinted from EuroIntervention 7/1, Gijsen et al., High shear stress induces a strain increase in human coronary plaques over a 6-month period, 121–127 [45], Copyright (2011), with permission from Europa Digital & Publishing).