Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug;146:31–41. doi: 10.1016/j.mod.2017.05.004

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 7 — Flk1-Cre Sox7^fl/fl embryos have severe and widespread vascular defects at E10.5. Whole mount PECAM1 staining of Sox7^fl/+ and Flk1-Cre Sox7^fl/fl embryos at E10.5. (A) 3D projection of embryo proper, white boxes indicate areas of magnification. Data shown are representative of 4 embryos. (B) Top panel: organization of capillaries in posterior region, bottom panel: vitelline artery (VA). (C) Sagittal slices through the embryo proper. DA: dorsal aorta, white arrow indicates length of functional dorsal aorta; yellow arrows indicate malformation of the DA. (D) Mean length of DA relative to embryo ± SEM, n = 6 control (Sox7^fl/+ and Sox7^fl/fl) versus n = 4 Flk1-Cre Sox7^fl/fl embryos. (E) Expression of FLK1 and TIE2 in wild type gastrulating embryos at early streak (left panel) and late streak (right panel) stages measured by flow cytometry.