Table 8.
Studied Parameters | Doses | ||||
---|---|---|---|---|---|
0- mg/kg | 0i mg/kg | 58 mg/kg | 116 mg/kg | 232 mg/kg | |
Serum Creatinine (mg/ dl) | 2.64 ± 0.19b | 5.00 ± 0.92a | 2.31 ± 0.88b | 2.62 ± 1.15b | 2.65 ± 0.97b |
Urine Creatinine (mg/ dl) | 25.35 ± 3.88a | 26.88 ± 2.28a | 25.85 ± 5.15a | 26.38 ± 3.64a | 28.09 ± 3.45a |
Total Cholesterol (mg/ dl) | 288.89 ± 14.43a | 285.26 ± 11.47a | 329.38 ± 13.53a | 335.90 ± 12.31a | 340.72 ± 5.16a |
HDL Cholesterol (mg/dl) | 58.60 ± 3.30a | 51.91 ± 4.36a | 65.21 ± 5.97a | 63.67 ± 3.87a | 62.50 ± 2.68a |
Atherosclerosis Index(mg/ dl) | 3.98 ± 0.86a | 4.58 ± 0.55a | 4.51 ± 0.12a | 4.78 ± 0.74a | 4.55 ± 1.07a |
Triglycerides (mg/dl) | 114.85 ± 7.09a | 102.46 ± 10.65a | 110.10 ± 7.92a | 119.64 ± 6.44a | 126.29 ± 5.94a |
Renal protein (mg/g) | 3.81 ± 0.95a | 3.67 ± 1.11a | 3.72 ± 1.07a | 3.98 ± 1.02a | 4.02 ± 0.29a |
Spleen protein (mg/g) | 72.73 ± 9.71a | 71.82 ± 8.40a | 75.55 ± 6.79a | 79.64 ± 9.58a | 84.36 ± 7.82a |
Pulmonary protein (mg/g) | 59.09 ± 3.02a | 42.81 ± 2.22b | 40.97 ± 4.26b | 41.58 ± 4.21b | 45.36 ± 3.86b |
Hepatic protein (mg/g) | 148.73 ± 2.70ab | 127.91 ± 12.18b | 134.82 ± 5.94b | 141.82 ± 6.31ab | 154.91 ± 13.08a |
Cardiac protein (mg/g) | 53.94 ± 5.08a | 40.03 ± 2.57b | 42.73 ± 2.49ab | 46.00 ± 6.08ab | 49.45 ± 4.71ab |
Serum protein (mg/g) | 413.36 ± 19.7a | 410.57 ± 12.60a | 395.39 ± 14.57b | 400.02 ± 17.01b | 402.91 ± 10.58b |
Urine protein (mg/g) | 3.64 ± 0.94a | 3.24 ± 0.20ab | 2.80 ± 0.14b | 3.28 ± 0.21ab | 3.15 ± 0.32ab |
ALAT (UI/l) | 30.36 ± 2.92b | 39.42 ± 3.51a | 34.86 ± 1.74ab | 41.92 ± 2.33a | 43.79 ± 2.44a |
ASAT (UI/l) | 55.19 ± 3.18a | 51.90 ± 4.21ab | 49.02 ± 3.49b | 53.88 ± 4.34ab | 57.11 ± 4.33a |
0-: Normal control, 0i: Infected and non-treated. Tabulated values are mean ± SEM of five trials. Values of the same row with different letters are significantly different at P < 0.05