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. 2017 Jul 3;216(7):2217–2230. doi: 10.1083/jcb.201601109

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© 2017 Stik et al.

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Figure 4. — RNA-seq analysis of the molecular signatures displayed by the stromal cells and the EV. (A) Workflow chart of the RNA-seq analysis. NGS, next-generation sequencing. (B and C) Global analysis of the small RNA (B) and poly-A–RNA (C) libraries. For the small RNA libraries, all the sequenced reads are represented, and for the poly-A–RNA libraries, only the most abundant genes (RPKM > 100) are represented. (D) PCA of the global miRNA (left) and poly-A RNA (right) transcriptomes.