Table 1.

Scope of Multicomponent Carboamination of Tethered Enynes with PhNNPh^a

	Substrate	% Isolated Yieldb (2:3)	1H NMR % Yield (2:3)
1a		50 (>99:1)	92 (85:15)
1b		86 (44:56)	92 (53:47)
1c		37 (>99:1)	–d
1d		13 (1: >99)e	29 (1: >99)
1e		60 (>99:1)	91 (>99:1)
1f		69 (>99:1)	86 (>99:1)
1g		50 (>99:1)	–d
1h		54 (49:51)	–d
1i		57 (5:95)f	–d
1j		36 (1:>99)g	–d
1k		37 (1:>99)h	–d
11		0	n.d.
1m		0	n.d.

^aLoading of [py₂TiCl₂NPh]₂ and reaction yields with respect to PhNNPh.

^bIsolated as the ketone product after hydrolysis. See SI for details.

^cDetermined by 1H NMR analysis of the crude reaction mixture.

^dCould not be determined due to peak overlap in the ¹H NMR spectrum.

^eIsolated as the retro-ene product 3d′ (Figure 3).

^fAs a mixture of 2i, 3i and 4i (Figure 5).

^gAs 4j.

^hAs a mixture of 3k and 4k.