. Author manuscript; available in PMC: 2018 May 1.

Published in final edited form as: Brain Behav Immun. 2017 Feb 24;62:332–343. doi: 10.1016/j.bbi.2017.02.018

Table 4. TEMPOL-fed healthy mice show altered distributions of lymphocyte subsets compared to controls.

Lymphoid organs were harvested and cells prepared following 28 days on control or TEMPOL feed. Values represent pooled results from 2 experiments, ±SD, with 13 mice per feed group.

	Control Average %	TEMPOL Average %	P value
Lymph node
% CD4⁺ T cells	49.4 ±1.6	45.1 ±3.2	0.001^*
% CD8⁺ T cells	42.1 ±1.1	47.1 ±2.6	<0.001^*
% CD4⁺CD25⁺Foxp3⁺ T cells	8.9 ±0.9	11.7 ±1.2	<0.001^*
Spleen
% CD4⁺ T cells	52.9 ±3.2	47.7 ±3.0	0.001^*
% CD8⁺ T cells	40.9 ±3.2	46.5 ±2.9	<0.001^*
% CD4⁺CD25⁺Foxp3⁺ T cells	7.0 ±0.6	6.1 ±0.6	0.003^*

Mann-Whitney Rank Sum test with uncorrected p values are shown for each subset analyzed in comparing control to TEMPOL fed animals, *p < 0.05. Bolded values are those withstanding Bonferroni correction for three populations analysed p < 0.0167.