Table 1.
Cohort Characteristics
| Variable | Thrombotic MI (N=11) | Non-Thrombotic MI (N=12) | Stable CAD (N=15) | p-value |
|---|---|---|---|---|
| Age (mean ± SD) yrs | 60.0 ± 17.7 | 56.3 ± 16.6 | 61.3 ± 8.9 | 0.66 |
| Males (%) | 63.6 | 41.7 | 53.3 | 0.17 |
| Caucasian Race (%) | 90.9 | 66.7 | 93.3 | 0.60 |
| Current Smoker (%) | 36.4 | 50.0 | 20.0 | 0.66 |
| History of Dyslipidemia (%) | 54.5 | 33.3 | 86.7 | 0.003 |
| History of Diabetes Mellitus (%) | 18.2 | 0.0 | 40.0 | 0.03 |
| History of Hypertension (%) | 63.6 | 75.0 | 93.3 | 0.35 |
| History of Atherosclerosis (%) (MI, CAD, PCI, CABG) | 27.3 | 33.3 | 100.0 | <0.0001 |
| History of Congestive Heart Failure (%) | 0.0 | 8.3 | 6.7 | 1.00 |
| History of Chronic Renal Failure (%) | 0.0 | 8.3 | 0.0 | 0.66 |
| History of Stroke (%) | 0.0 | 25.0 | 0.0 | 0.05 |
| HR at time of presentation (mean ± SD) | 80.6 ± 10.1 | 88.3 ± 27.5 | 65.9 ± 9.6 | 0.01 |
| SBP at time of presentation (mean ± SD) | 138.1 ± 30.6 | 124.0 ± 31.9 | 133.4 ± 16.5 | 0.43 |
| DBP at time of presentation (mean ± SD) | 84.2 ± 20.3 | 81.2 ± 25.1 | 70.3 ± 15.3 | 0.19 |
| MAP at time of presentation (mean ± SD) | 102.2 ± 22.7 | 95.4 ± 26.9 | 91.4 ± 14.3 | 0.45 |
| BMI at time of presentation (mean ± SD) | 29.3 ± 7.2 | 27.8 ± 6.7 | 33.0 ± 7.1 | 0.15 |
| Time (hours) from presentation to T0 (median ± IQR) | 1.4 ± 1.4 | 17.6 ± 9.8 | NA | <0.0001 |
| Time (hours) symptoms to T0 (median ± IQR) | 8.4 ± 26.1 | 20.2 ± 17.6 | NA | 0.19 |
| Baseline Troponin (median ± IQR) | 0.48 ± 5.64 | 1.64 ± 2.23 | 0.01 ± 0.00 | <0.0001 |
| Peak Troponin (median ± IQR) | 46.57 ± 71.00 | 2.06 ± 4.14 | 0.01 ± 0.00 | <0.0001 |
| Glucose at Baseline (median ± IQR) | 143.0 ± 71.0 | 103.5 ± 32.5 | 115.0 ± 44.0 | 0.03 |
| Creatinine at Baseline (median ± IQR) | 0.90 ± 0.42 | 0.80 ± 0.65 | 0.90 ± 0.24 | 0.68 |
| Platelets at Baseline (mean ± SD) | 189.4 ± 80.1 | 217.6 ± 64.9 | 236.4 ± 54.5 | 0.21 |
| ST Elevation on EKG at Baseline | 90.9 | 25.0 | 0.0 | <0.0001 |
| At least one vessel with >50% Coronary Stenosis on Enrollment Angiogram | 100.0 | 25.0 | 66.7 | 0.0004 |
| PCI at time of Enrollment | 100.0 | 0.0 | 13.3 | <0.0001 |
| Aspirin use at time of Enrollment (%) | 100.0 | 91.7 | 86.7 | 0.77 |
| P2Y12 Inhibitors use at Enrollment (%) | 63.6 | 50.0 | 60.0 | 0.84 |
Abbreviations used in table
MI: Myocardial Infarction; CAD: Coronary Artery Disease; PCI: percutaneous coronary intervention;
CABG: coronary artery bypass graft; HR: heart rate; SBP: systolic blood pressure;
DBP: diastolic blood pressure; MAP: mean arterial pressure; BMI: body mass index;
IQR: Inter-quartile range; EKG: electrocardiogram