Table 1.

Studies of subthreshold psychotic syndrome in 22q11.2 deletion syndrome (22q11.2DS).

	Age in years Age Range	N	Definition of Prodromal Syndrome	Source of Information	Rates of Prodromal Symptoms
Stoddard et al. 2010	15.1 (4.3) 12 – 22	20	At least one positive symptom scored ≥3 on SIPS	Participants and caregivers interviewed together	45%
Antshel et al. 2010	15.0 (1.9) 12.0–19.9	70	At least one positive symptom scored ≥3 on SIPS	Participants and caregivers interviewed collaterally	20%
Shapiro et al. 2011	17.5 (2.5) 14 – 22	23	At least one positive symptom scored ≥3 on SIPS	Participants and caregivers interviewed collaterally	56.5%
Schneider et al. 2012	15.4 (2.3) 11 – 20	47	At least one positive symptom scored ≥3 or at least one negative symptom scored ≥3 on SIPS	Participants only	83% negative 40.4% positive
Tang et al. 2014	15.2 (4.8) 8 – 25	157	At least one positive symptom scored 3 – 5 or at least two negative or disorganized symptoms scored ≥3 on SIPS	Participants and caregivers interviewed collaterally	44% positive 54% positive or negative

Mean (SD); SIPS – The Structured Interview for Prodromal Symptoms.