Table 1.
Patient's demographics according to STXBP4 expression
| Variables | STXBP4 |
ΔNp63 |
p63 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| High No. (%) |
Low No. (%) |
P-value | Positive No. (%) |
Negative No. (%) |
P-value | Positive No. (%) |
Negative No. (%) |
P-value | |
| Age | 0.42 | 0.051 | 0.22 | ||||||
| ≤ 65yr | 9 (10.3) | 9 (10.3) | 10 (11.5) | 8 ( 9.2) | 16 (18.4) | 2 ( 2.3) | |||
| > 65 yr | 43 (50.5) | 26 (29.9) | 20 (23.0) | 49 (56.3) | 51 (58.6) | 18 (20.7) | |||
| Sex | 0.70 | 0.69 | < 0.99 | ||||||
|
| |||||||||
| Male | 47 (54.0) | 33 (37.9) | 27 (31.0) | 53 (60.9) | 61 (70.1) | 19 (21.8) | |||
| Female | 5 ( 5.7) | 2 ( 2.3) | 3 ( 3.4) | 4 ( 4.6) | 6 ( 4.6) | 1 ( 3.4) | |||
|
| |||||||||
| Differentiation | 0.080 | 0.034 | 0.24 | ||||||
| Well or Moderately | 43 (49.4) | 23 (26.4) | 27 (31.0) | 39 (44.8) | 53 (60.9) | 13 (15.0) | |||
| Poorly | 9 (10.3) | 12 (13.8) | 3 ( 3.4) | 18 (20.7) | 14 (16.1) | 7 ( 8.0) | |||
|
| |||||||||
| T factor | < 0.001 | 0.33 | < 0.001 | ||||||
| T1 | 8 (9.2) | 19 (21.8) | 7 ( 8.0) | 20 (23.0) | 27 (31.0) | 0 ( 0.0) | |||
| T2-3 | 44 (50.6) | 16 (18.4) | 23 (26.4) | 37 (42.5) | 40 (46.0) | 20 (23.0) | |||
|
| |||||||||
| N factor | > 1 | > 1 | 0.28 | ||||||
| N0 | 36 (41.4) | 25 (28.7) | 21 (24.1) | 40 (46.0) | 49 (56.3) | 12 (13.8) | |||
| N1-2 | 16 (18.4) | 10 (11.5) | 9 (10.3) | 17 (19.5) | 18 (20.7) | 8 ( 9.2) | |||
|
| |||||||||
| Disease stage | 0.030 | 0.37 | 0.20 | ||||||
| I | 23 (26.4) | 24 (27.6) | 14 (16.1) | 33 (37.9) | 39 (44.8) | 8 ( 9.2) | |||
| II-III | 29 (33.3) | 11 (12.6) | 16 (18.4) | 24 (27.6) | 28 (32.2) | 12 (13.8) | |||
|
| |||||||||
| Pleural Involvement | 0.028 | 0.66 | 0.29 | ||||||
| Positive | 30 (34.5) | 11 (12.6) | 13 (14.9) | 28 (32.2) | 30 (34.5) | 11 (13.8) | |||
| Negative | 22 (25.3) | 24 (27.6) | 17 (19.5) | 29 (33.3) | 37 (42.5) | 9 (10.3) | |||
|
| |||||||||
| Lymphatic permeation | 0.83 | > 1 | 0.61 | ||||||
| Positive | 29 (33.3) | 18 (20.7) | 16 (18.4) | 31 (35.6) | 35 (40.2) | 12 (13.8) | |||
| Negative | 23 (26.4) | 17 (19.5) | 14 (16.1) | 26 (29.9) | 32 (36.8) | 8 ( 9.2) | |||
|
| |||||||||
| Vascular invasion | 0.39 | > 1 | > 1 | ||||||
| Positive | 26 (29.9) | 14 (16.1) | 14 (16.1) | 26 (29.9) | 31 (35.6) | 9 (10.3) | |||
| Negative | 26 (29.9) | 21 (24.1) | 16 (18.4) | 31 (35.6) | 36 (41.4) | 11 (12.6) | |||
*
P-values were obtained by Fisher's exact test.
†
Clinical stage at the time of initial diagnosis was determined according to the seventh edition of General Rule for Clinical and Pathological Record of Lung Cancer (2010), the Japan Lung Cancer Society.