Table 6.
Differences in the Vibration Thresholds, Grip Strength, Pegboard Test, Heel Lift, Balance, and Reflexes in the Dominant Extremities Between Cancer Survivors With (n=426) and Without (n=197) Chemotherapy Induced Neuropathy (CIN)
| Site | No CIN 31.6% (n=197) |
CIN 68.4% (n=426) |
t-test,* p-value | A % |
B % |
|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | ||||
| Vibration Thresholds (volts) | |||||
| Dorsal IP joint of great toe | 17.01 (10.64) | 25.14 (14.66) | −8.06, <.001 | 1.5 | 8.0 |
| Medial malleolus | 20.98 (11.23) | 28.10 (13.53) | −6.85, <.001 | 2.1 | 9.0 |
| Patella | 22.12 (10.80) | 27.26 (11.90) | −5.31, <.001 | 1.5 | 3.3 |
| Dorsal IP joint of thumb | 5.19 (2.26) | 6.92 (4.56) | −6.31, <.001 | 0.0 | 0.0 |
| Dorsal IP joint of index finger | 5.77 (3.10) | 7.44 (4.56) | −5.32, <.001 | 0.0 | 0.0 |
| Ulnar prominence of the wrist | 6.99 (2.81) | 9.18 (5.51) | −6.52, <.001 | 0.0 | 0.0 |
| Lateral epicondyle | 10.33 (4.31) | 12.71 (6.23) | −5.49, <.001 | 0.0 | 0.0 |
| Additional Tests | |||||
| Grip strength (kilograms) | 27.70 (8.01) | 25.39 (8.28) | 3.25, .001 | n/a | |
| Number of pins in 30 seconds | 14.63 (2.48) | 14.04 (2.26) | 2.92, .004 | n/a | |
| Heel lift (seconds) | 14.16 (2.98) | 12.63 (4.56) | 4.97, <.001 | n/a | |
| Timed get up and go test (seconds) | 6.57 (1.51) | 7.75 (2.49) | −7.27, <.001 | n/a | |
| Fullerton Advanced Balance test | 36.17 (4.77) | 33.25 (6.69) | 6.18, <.001 | n/a | |
| Achilles reflex (% (n) absent) | 54.2 (104) | 78.2 (326) | FE, <.001 | n/a | |
*
Independent sample t-test
Abbreviations: A = Percentage of cancer survivors without CIN who did not feel the maximum vibration threshold, B = Percentage of cancer survivors with CIN who did not feel the maximum vibration threshold, IP = interphalangeal, n/a = not applicable, SD = standard deviation