Table 7.

Differences in Muscle Strength Testing in the Dominant Lower and Upper Extremities Between Cancer Survivors With (n=426) and Without (n=197) Chemotherapy Induced Neuropathy (CIN)

Location	Extremity	0⁺	1⁺	2⁺	3⁺	4⁺	5⁺	p-value^*
Location	Extremity	% (n)	% (n)	% (n)	% (n)	% (n)	% (n)	p-value^*
Extension of great toe	No CIN	0.0 (0)	0.0 (0)	0.0 (0)	0.0 (0)	5.1 (10)	94.9 (185)	<.001
Extension of great toe	CIN	0.7 (3)	0.9 (4)	1.4 (6)	2.8 (12)	16.8 (71)	77.3 (327)	<.001
Dorsiflexion of ankle	No CIN	0.5 (1)	0.0 (0)	0.0 (0)	0.0 (0)	1.0 (2)	98.5 (192)	.004
Dorsiflexion of ankle	CIN	0.5 (2)	0.0 (0)	0.2 (1)	1.2 (5)	5.2 (22)	92.9 (393)	.004
Plantar flexion of ankle	No CIN	0.5 (1)	0.0 (0)	0.0 (0)	0.0 (0)	2.6 (5)	96.9 (188)	.010
Plantar flexion of ankle	CIN	0.5 (2)	0.0 (0)	0.2 (1)	1.4 (6)	6.6 (28)	91.2 (385)	.010
Abduction of the little finger	No CIN	0.0 (0)	0.0 (0)	0.5 (1)	0.5 (1)	13.3 (26)	85.6 (167)	<.001
Abduction of the little finger	CIN	0.0 (0)	0.0 (0)	1.7 (7)	5.9 (25)	23.6 (100)	68.8 (291)	<.001
Opposition of thumb and little finger	No CIN	0.0 (0)	0.0 (0)	0.5 (1)	1.0 (2)	3.6 (7)	94.9 (185)	<.001
Opposition of thumb and little finger	CIN	0.2 (1)	0.0 (0)	1.2 (5)	4.5 (19)	15.1 (64)	79.0 (334)	<.001
Wrist extension	No CIN	0.0 (0)	0.0 (0)	0.0 (0)	0.0 (0)	2.1 (4)	97.9 (191)	.001
Wrist extension	CIN	0.0 (0)	0.2 (1)	0.7 (3)	1.4 (6)	7.3 (31)	90.3 (381)	.001

Mann Whitney U test

⁺

Medical Research Council Scale: 0=no flicker of movement, 1=visible contraction without movement of the site, 2=movement of the site but not against gravity, 3=movement over the full range against gravity, 4=movement against gravity and resistance, 5=normal