Table 2.
Average response time (in seconds) of different parts of P. latifolia Roxb. and standard in the tail flick model.
| Group | Dose (mg/kg) | Mean basal reading ± S.E.M | Mean reaction time (sec) ± S.E.M (percentage reaction time) |
||||
|---|---|---|---|---|---|---|---|
| 15 min | 30 min | 45 min | 60 min | 120 min | |||
| Control | Vehicle | 2.23 ± 0.15 | 2.30 ± 0.17 | 2.40 ± 0.12 | 2.27 ± 0.18 | 2.47 ± 0.15 | 2.31 ± 0.14 |
| Pentazocine | 15 | 3.11 ± 0.38 | 4.85 ± 0.21 (25.25) | 7.35 ± 0.29 (61.54) | 6.5 ± 0.46 (49.20) | 6.05 ± 0.36 (42.71) | 4.84 ± 0.19 (25.21) |
| Whole root | 100 | 2.95 ± 0.45 | 3.46 ± 0.38a (7.23) | 4.50 ± 0.46a (22.0) | 4.70 ± 0.45 (24.82) | 4.30 ± 0.22 (19.14) | 4.07 ± 0.44 (15.88) |
| 200 | 2.6 ± 0.39 | 3.58 ± 0.45a (13.24) | 4.26 ± 0.30a (22.42) | 5.44 ± 0.46 (38.37) | 4.4 ± 0.42a (24.3) | 3.96 ± 0.35 (18.3) | |
| 400 | 2.38 ± 0.15 | 3.46 ± 0.38a (14.17) | 4.55 ± 0.46a (28.47) | 5.67 ± 0.33 (43.17) | 4.93 ± 0.22 (33.46) | 4.0 ± 0.43 (21.25) | |
| Stem | 100 | 2.14 ± 0.40 | 2.40 ± 0.21a (3.35) | 2.30 ± 0.31ab (13.86) | 4.03 ± 0.35ab (24.04) | 3.49 ± 0.35ab (17.17) | 2.81 ± 0.32a (14.75) |
| 200 | 2.60 ± 0.42 | 3.25 ± 0.40 (8.78) | 4.10 ± 0.35a (20.27) | 4.35 ± 0.42a (23.64) | 4.65 ± 0.39 (27.70) | 3.72 ± 0.46 (17.43) | |
| 400 | 2.0 ± 0.25 | 3.04 ± 0.16a (13.0) | 3.83 ± 0.31a (22.8) | 4.11 ± 0.40ab (26.3) | 4.57 ± 0.35a (32.12) | 3.44 ± 0.36a (18.0) | |
| Leaf | 100 | 2.51 ± 0.63 | 3.13 ± 0.34a (8.22) | 3.71 ± 0.44ac (16.02) | 4.51 ± 0.44a (26.7) | 3.96 ± 0.34a (19.35) | 3.81 ± 0.43 (17.35) |
| 200 | 2.7 ± 0.17 | 3.53 ± 0.21 (11.36) | 4.35 ± 0.36a (22.6) | 5.29 ± 0.41 (35.47) | 4.43 ± 0.45a (23.69) | 3.93 ± 0.44 (16.84) | |
| 400 | 2.5 ± 0.41 | 3.55 ± 0.38 (14.0) | 4.77 ± 0.38a (30.26) | 5.62 ± 0.37c (41.6) | 5.01 ± 0.44 (33.46) | 4.03 ± 0.36 (20.4) | |
Values are expressed as mean ± SEM. Statistical analysis was done by two-way ANOVA followed by Bonferroni-test (p < 0.05). a when compared with pentazocine, b when compared with whole root and c when compared with whole stem.