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Time‐courses of (a) glucose, (b) immunoreactive insulin (IRI) and (c,d) mannose levels in plasma during the 75‐g oral glucose tolerance test in participants with normal glucose tolerance (NGT; open circle, n = 5), impaired glucose metabolism (IGM; closed triangle, n = 5) and diabetes (DM; closed circle, n = 5). Samples of five participants among 25 participants belonging to each group were randomly chosen. *P < 0.01 vs NGT; **P < 0.05 vs NGT.
