Skip to main content
. 2017 Feb 28;8(4):434–445. doi: 10.1111/jdi.12603

Figure 8.

Figure 8

Reactive oxygen species (ROS) inhibitor suppresses the high glucose (HG)‐induced overexpressions of p38 mitogen‐activated protein kinase (MAPK), extracellular signal‐regulated protein kinase 1/2 (ERK1/2) and leptin in H9c2 cells. Cells were priority treated with 1,000 μmol/L N‐actyl‐L‐cystine for 60 min with or without HG. (a,c,e) The expressions of leptin, p38 and ERK1/2 were measured by western blot analysis. (b,d,f) Densitometric analysis of the related protein expression levels in (a,c,e), respectively. Data are shown as mean ± standard error of the mean (n = 3). **P < 0.01 vs the control (Con) group; ‡ P < 0.01 vs the HG‐treated group. GAPDH, glyceraldehyde 3‐phosphate dehydrogenase; p‐p38, phosphorylated‐p38; t‐p38, total p38.