Table 1.
Characteristics of the included studies on the association between TCF7L2 and gestational diabetes mellitus risk
| Author, (year) reference | Ethnicity | Country | Mean age (cases/controls) | Genotyping method | GDM criteria |
|---|---|---|---|---|---|
| Aris, (2012)27 | Asian | Malaysia | 29.7/28.5 | NA | ADA |
| Cho, (2009)17 | Asian | Korea | 32/64.7 | Allelic discrimination assay | IWCGDM |
| de Melo, (2015)26 | Hispanic/Latino | Brazil | 32/24 | SNP Genotyping Assay | ADA |
| Freathy, (2010)12 | Mixed | Australia and UK | NA | Illumina Golden Gate platform | OGTT |
| Kan, (2014)15 | Asian | China | 30.7/30.9 | Allelic discrimination assay | OGTT |
| Huerta‐Chagoya, (2015)25 | Hispanic/Latino | Mexico | 35/28 | SNP genotype (LGC) | OGTT |
| Hui, (2011)32 | Asian | China | 32/30 | PCR‐LDR | OGTT |
| Klein, (2012)19 | Caucasian | Australia | 28.2/30.1 | NA | OGTT |
| Liu, (2014)33 | Asian | China | 31.88/28.78 | Mass spectrometry | OGTT |
| Pagan, (2014)29 | Caucasian | Spain | 34.31/31.2 | Sequencing | OGTT |
| Papadopoulou, (2011)20 | Caucasian | Sweden | NA | TaqMan allelic discrimination assay | OGTT |
| Reyes‐López, (2014)21 | Mexican | Mexico | 29/31 | PCR | ADA |
| RIZK, (2011)16 | Caucasian | Qatar | NA | TaqMan allelic discrimination assay | NA |
| Shaat, (2007)14 | Caucasian | Scandinavia | 32.3/30.5 | TaqMan allelic discrimination assay | OGTT |
| Shi, (2014)28 | Asian | China | 30/29 | AS‐PCR | OGTT |
| Stuebe, (2014)31 | African‐American | USA | 24.1 (total) | Sequenom iPLEX platform | OGTT |
| Thomas, (2014)24 | Asian | India | NA | NA | NA |
| Vcelak, (2012)18 | Caucasian | Czech Republic | 32.8/29.9 | TaqMan allelic discrimination assay | WHO |
| Wang, (2013)39 | Asian | China | NA | PCR‐LDR | OGTT |
| Watanabe, (2007)30 | Mexican‐American | USA | 35.0/33.4 | TaqMan allelic discrimination assay | OGTT |
| Zhang, (2015)23 | Asian | China | 30.58/28.75 | PCR‐RFLP | OGTT |
ADA, American Diabetes Association; AS‐PCR, allele‐specific polymerase chain reaction; GDM, gestational diabetes mellitus; IWCGDM, International Workshop‐Conference on Gestational Diabetes Mellitus; LGC, LGC Bioresearch Technologies; OGTT, oral glucose tolerance test; NA, not available; PCR, polymerase chain reaction; PCR‐LDR, ligase detection reaction–polymerase chain reaction; SNP, single nucleotide polymorphism; WHO, World Health Organization.